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X4-tropic virus
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med.
A strain of HIV that enters and infects a host cell by binding to the CXCR4 receptor on the host cell. To enter a host cell, HIV must first attach to a CD4 receptor, then attach to either the CCR5 or CXCR4 receptor, and finally fuse its membrane with the host cell membrane. HIV is usually R5-tropic
uses CCR5
during the early stages of infection, but the virus may later switch to using either CXCR4 or both CCR5 and CXCR4.
see also
CD4 receptor
,
CXCR4
,
dual-tropic virus
,
R5-tropic virus
X4
:
1 phrase
in 1 subject
Abbreviation
1
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