| insulin resistance |
The body's decreasing ability to respond to and use the insulin it produces. As a result, excess glucose builds up in the blood (hyperglycemia) Insulin resistance increases the risk of developing type 2 diabetes and heart disease. Use of certain antiretroviral (ARV) drugs may cause insulin resistance. |
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| insulin sensitivity |
The degree to which the body's cells respond to insulin and take up glucose from the blood. |
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| iPSA |
intact PSA |
vlad-and-slav |
| integrase |
An enzyme found in HIV (and other retroviruses) HIV uses integrase to insert (integrate) its viral DNA into the DNA of the host cell. Integration is a crucial step in the HIV life cycle and is targeted by a class of antiretroviral (ARV) HIV drugs called integrase strand transfer inhibitors (INSTIs) |
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| integrase inhibitor |
Antiretroviral (ARV) HIV drug class. Integrase strand transfer inhibitors (INSTIs) block integrase (an HIV enzyme) HIV uses integrase to insert (integrate) its viral DNA into the DNA of the host cell. Blocking integrase prevents HIV from replicating. |
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| integrase strand transfer inhibitor (INSTI) |
Antiretroviral (ARV) HIV drug class. Integrase strand transfer inhibitors (INSTIs) block integrase (an HIV enzyme) HIV uses integrase to insert (integrate) its viral DNA into the DNA of the host cell. Blocking integrase prevents HIV from replicating. |
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| integration |
The third of seven steps in the HIV life cycle. During integration, HIV uses integrase (an HIV enzyme) to insert its viral DNA into the DNA of the host cell. |
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| Intelligence Pressure Release |
IPR |
iwona |
| Intense Pain |
IP |
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| intensification |
Adding additional antiretroviral (ARV) drugs to an HIV regimen to further reduce replication of HIV |
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| Intensive Psychiatric Rehabilitation Treatment |
IPRT |
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| Intensive Special Care Unit |
ISCU |
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| interferon (IFN) |
Cytokines secreted by certain cells in response to an antigen, usually a virus. Interferon signals neighboring cells into action and inhibits the growth of malignant cells. There are three types of interferons: alpha, beta, and gamma. Laboratory-made interferons are used to treat certain cancers and opportunistic infections. |
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| interleukin-2 (IL-2) |
A cytokine that stimulates the growth and replication of immune cells, specifically B lymphocytes (B cells) and T lymphocytes (T cells) Laboratory-made interleukin-2 (IL-2) is used to treat certain cancers. |
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| interleukin-7 (IL-7) |
A cytokine that prompts the immune system to make more B lymphocytes (B cells) and T lymphocytes (T cells) Laboratory-made interleukin-7 (IL-7) coupled with antiretroviral therapy (ART) is being studied as a potential treatment for HIV |
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| Intermittent claudication |
IC |
iwona |
| Intermittent Peritoneal Dialysis |
IPD |
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| Intermittent Positive Pressure Breathing |
IPPB |
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| Internal Value Structure |
IVS |
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| international maternal pediatric adolescent AIDS clinical trials (IMPAACT) group |
A cooperative group of institutions, investigators, and other collaborators organized to evaluate treatment for HIV-infected children, adolescents, and pregnant women, including treatment and prevention of coinfections; to develop and evaluate safe and effective approaches to prevent mother-to-child transmission of HIV; and to evaluate vaccines for the prevention of HIV transmission among adolescents. International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group was formed through a merger of investigators, including investigators from the Pediatric AIDS Clinical Trials Group (PACTG) |
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